First Appearance: Batman Arkham Asylum
Smilex or "Joker Toxin\ Happy Gas" is a chemical developed by the Joker, which he used as a weapon in his first attack on Gotham, using it to poison the manager of the Gotham Merchant's Bank.
The toxin is airbourne and it caused her great pain, foricng her to laugh. The laughter was actually the sound of her dying and the more hysterically she laughed, the closer she was to death.
The toxin left her with a permanent Joker grin on it's victim's face. She was either the first or the first recorded fatality of the gas.
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